Santa Barbara Police are actively reviewing video surveillance tape at the Sansum Clinic Prescription Pharmacy on Pesetas lane near Calle Real after a break-in over the weekend.
Painkillers were taken but specifics were not released by investigators.
It's unknown if more than one suspect was involved.
Sansum officials believe the crime occurred very quickly.
There have also been similar break ins at nearby local pharmacies in Camarillo and Ventura. Painkillers were also taken in those crimes.